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KMID : 0613820080180020220
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Journal of Life Science
2008 Volume.18 No. 2 p.220 ~ p.227
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Antioxidant Activities of the Solvent Extracts from Tetragonia tetragonioides
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Lee Min-A
Choi Hye-Jung
Kang Jum-Soon
Choi Young-Hwan
Joo Woo-Hong
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Abstract
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To clarify the antioxidation effect of the various solvent fractionation of Tetragonia tetragoniodes which has been known to superior plants for the traditional prevention and treatment of stomach-related diseases, total polyphenol and flavonoid contents, vitamin E content, the elimination activity of a DPPH free radical and superoxide anion, inhibition activity of the superoxide generation, reducing power and metal chelating effects were estimated. The contents of the polyphenol compounds were highest in the DCM and EA fractionation, and the content of flavonoid was high in the order of HX and EA fractionation. The vitamin E content showed high in the order of the HX and DCM fractionation among solvent fractions. IC50 for the elimination effect of a DPPH radical were estimated as 554.25 and 394.96 ug/ml in the DCM and EA fractions, respectively. These values were higher than that of BHT widely used in antioxidation effect. The inhibition activity of the superoxide generation using the T. tetragoniodes solvent fractions represented the effects similar to that of -tocopherol known to prevent the lipoprotein oxidation, but lower consequences than that of the phenol-resins, BHT784.7ug/ml and BHA, respectively. In the antioxidation activity derived by the reducing capability, the EA fractionation in a 1.5 mg/ml concentration showed higher than that of -tocopherol.
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KEYWORD
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Tetragonia tetragonioides, solvent extract, antioxidant activity
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